| Home | Teams and Players | Homerun Kings | Top Salaries | Most Runs Batted In | Hall of Fame |
| Ranking | Player | Total Home Runs | Total Across Regular Seasons |
|---|---|---|---|
| 1 | Barry Bonds | 771 | 762 |
| 2 | Hank Aaron | 761 | 755 |
| 3 | Babe Ruth | 729 | 714 |
| 4 | Alex Rodriguez | 709 | 696 |
| 5 | Willie Mays | 661 | 660 |
| 6 | Ken Griffey | 636 | 630 |
| 7 | Jim Thome | 629 | 612 |
| 8 | Sammy Sosa | 611 | 609 |
| 9 | Albert Pujols | 610 | 591 |
| 10 | Frank Robinson | 596 | 586 |
| 11 | Mark McGwire | 588 | 583 |
| 12 | Manny Ramirez | 584 | 555 |
| 13 | Reggie Jackson | 581 | 563 |
| 14 | Harmon Killebrew | 576 | 573 |
| 15 | Rafael Palmeiro | 573 | 569 |
| 16 | David Ortiz | 558 | 541 |
| 17 | Mickey Mantle | 554 | 536 |
| 18 | Mike Schmidt | 552 | 548 |
| 19 | Jimmie Foxx | 538 | 534 |
| 20 | Frank Thomas | 524 | 521 |
| 21 | Willie McCovey | 524 | 521 |
| 22 | Ted Williams | 521 | 521 |
| 23 | Gary Sheffield | 515 | 509 |
| 24 | Mel Ott | 515 | 511 |
| 25 | Eddie Murray | 513 | 504 |